Product Name :
2-Deoxy-D-galactose (CAS 1949-89-9)
Synonym :
2-Deoxy-β-D-lyxo-hexose
Application :
2-Deoxy-D-galactose is an analog of hexose that inhibits fucosylation
CAS:
1949-89-9
Purity:
Molecular Weight:
164.20
Formula :
C6H12O5
Physical state:
Solid
solubility :
Soluble in water.
Shipping Condition :
Store at 4° C
Melting point:
107-110° C (lit.)
SMILES:
C(C=O)[C@H]([C@H]([C@@H](CO)O)O)O
References:
:Transport and phosphorylation of 2-deoxy-D-galactase in renal cortical cells. | Kleinzeller, A. and McAvoy, EM. 1976. Biochim Biophys Acta. 455: 126-43. PMID: 10999Incorporation of the hexose analogue 2-deoxy-D-galactose into membrane glycoproteins in HepG2 cells. | Geilen, CC., et al. 1992. Arch Biochem Biophys. 296: 108-14. PMID: 1318686A novel galactosyl-binding lectin from the plasma of the blood clam, Anadara granosa (L) and a study of its combining site.7-(Diethylamino)-2H-chromen-2-one Formula | Dam, TK., et al. 1992. Mol Cell Biochem. 117: 1-9. PMID: 1480160Direct selection of galactokinase-negative mutants of Candida albicans using 2-deoxy-galactose. | Gorman, JA., et al. 1992. Curr Genet. 21: 203-6. PMID: 1563045Enhanced development of morphine tolerance in rats treated with 2-deoxy-D-galactose. | Richter, P., et al. 1991. Psychopharmacology (Berl). 104: 279-83. PMID: 1876672The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP. | Krug, M., et al. 1991. Brain Res. 540: 237-42. PMID: 2054616Phenylboronic acid esters of the common 2-deoxy-aldoses. | Hess, D. and Klüfers, P. 2011. Carbohydr Res. 346: 1752-9. PMID: 21816393Optimal 2-[(18)F]fluoro-2-deoxy-D-galactose PET/CT protocol for detection of hepatocellular carcinoma. | Horsager, J., et al. 2016. EJNMMI Res. 6: 56.(S)-SPINOL manufacturer PMID: 27341819Saccharide binding by intelectins.PMID:33486519 | Sharma, S. and Ramya, TNC. 2018. Int J Biol Macromol. 108: 1010-1016. PMID: 29113893Amnesic action of 2-deoxy-D-galactose is not related to alterations in the release of dopamine and noradrenaline. | Schröder, H., et al. 1988. Biomed Biochim Acta. 47: 813-6. PMID: 32403102-D-gal Targets Terminal Fucosylation to Inhibit T-cell Response in a Mouse Skin Transplant Model. | Mao, K., et al. 2023. Transplantation. 107: 1291-1301. PMID: 36367925Consequences of recurrent phosphate trapping induced by repeated injections of 2-deoxy-D-galactose. Biochemical and morphological studies in rats. | Lattke, H., et al. 1979. Virchows Arch B Cell Pathol Incl Mol Pathol. 30: 297-312. PMID: 43010Synthesis of 2-deoxy-D-galactose containing gangliosides in vivo. | Hwang, YH., et al. 1993. FEBS Lett. 327: 63-7. PMID: 8335096Metabolism of 2-deoxy-D-galactose results in the accumulation of 2-deoxy-D-galactose 1-phosphate in brain. | Starling, JJ. and Keppler, DO. 1977. J Neurochem. 29: 603-4. PMID: 8943152-Deoxy-D-galactose effects on passive avoidance memorization in the rat. | Lorenzini, CG., et al. 1997. Neurobiol Learn Mem. 68: 317-24. PMID: 9398591Transport of 2-deoxy-D-galactose in Saccharomyces fragilis. | Jaspers, HT. and Van Steveninck, J. 1976. Biochim Biophys Acta. 443: 243-53. PMID: 953017