Product Name :
UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67]
Predicted band size :
20 kDa
Observed band size :
20 kDa
Synonyms:
Cyclin selective ubiquitin carrier protein antibody dJ447F3.2 antibody Mitotic specific ubiquitin conjugating enzyme antibody UB E2C antibody UBCH 10 antibody UbcH10 antibody UBE 2C antibody Ube2c antibody UBE2C_HUMAN antibody Ubiquitin carrier protein C antibody 展开
Function :
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ‘Lys-11’- and ‘Lys-48’-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating ‘Lys-11’-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.7-Bromo-3-oxoisoindoline-4-carbonitrile In stock Component of the APC/C complex, composed of at least 14 distinct subunits that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa. Within this complex, directly interacts with ANAPC2.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human UBE2C aa 80-179 / 179.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE38-67
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃.3-Methyl-1H-indazole-5-carboxylic acid Data Sheet Avoid repeated freeze / thaw cycles.PMID:33682914
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 20 kDa
Positive control :
HeLa cell lysate, HEK-293 cell lysate, THP-1 cell lysate.